Monckeberg’s sclerosis is a poorly understood condition associated with . Monckeberg’s sclerosis can coexist with atherosclerotic disease. Carlos Eduardo Barra Couri,1 Geruza Alves da Silva,1 José Antônio Baddini Martinez,1 Mönckeberg’s sclerosis (MS) is a degenerative and apparently .. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Mönckeberg sclerosis (MS) is a calcification of the me- dial layer of . ”Typical morphology of such calcifications in the early stages of the disease is linear de- posits along the . arteries in the absence of atherosclerotic plaque. Mayo Clin.
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It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. Recent studies, however, have demonstrated that MS is a risk factor for cardiovascular disease and peripheral artery obstruction [ 145 ].
A transesophageal echocardiogram was carried out, which reported segmental contractility disorders and valve leaflets without the presence of vegetations, but with multiple atheromatous plaques in the entire aortic trajectory. Extensive calcifications of the bilateral lingual and facial arteries are noted arrows as well as calcific plaques at bilateral carotid tree area arrow heads. The images were interpreted by a board-certified oral and maxillofacial radiologist.
The authors declare that no patient data appear in this article. Monckeberg’s sclerosis stands among the differential diagnoses of vasculitis, however, its clinical relevance has been undervalued due to the low clinical impact attributed to it and the low reported incidence, being considered as a condition secondary to a process of deposit of inert calcium. It is, however, a benign condition as it does not involve the intimal layer of the artery, and the lumen is kept open by the rigid media.
Clin J Am Soc Nephrol, 3pp. Differential diagnoses are mainly given by vasculitis affecting these vessels, among them, polyarteritis nodosa and giant cell arteritis.
Since the condition does not involve primarily the intimal layer of the artery, the lumen is kept open by the rigid media and, therefore, arterjosclerosis narrowing is not a direct consequence [ 1 – 4 ]. No lymph nodes were palpable and hoarseness was evident.
Discrimination between calcified triticeous cartilage and calcified carotid atheroma on panoramic radiography. There were no other risk factors for ischaemic heart disease. Greene for revision of the English text. Clinical and laboratory findings excluded any kind of rheumatologic disease such as dermatomyositis, scleroderma or systemic lupus erythematosus.
Clin J Am Soc Nephrol ; 3: Although the use of calcium chelators such as sodium thiosulfate has been proposed, the few available studies have failed to show significant results. Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. Further studies of the etiopathogenesis of this disease are needed.
monckebberg In other cases, as in ours, the impairment is so diffuse, thick and calcified that arteriosclerosis makes clamping and arterial revascularization impossible, being determinant for the indication of primary amputation.
Monckeberg, but according to histopathologic studies, it seems to be equally implied. The pathogenesis and natural history of Monckeberg’s sclerosis are briefly discussed. It commonly occurs in peripheral arteries of the lower limbs. Although one can argue about the possible role of upper airway obstruction mknckeberg intensifying the local deposition of calcium in the soft tissue of the pharynx, the diagnosis of MS was well documented in this case.
Please cite this article as: His lower limb vessels were screened during fluoroscopy and revealed no calcification figure 2. The authors declare that they have followed the protocols of their work center on the publication of patient data. There was little clinical response to management, and subsequently the patient started having sudden respiratory distress ruling out PTE, but with hypotension and persistent fever, and for this reason blood cultures were carried out which evidenced Klebsiella pneumoniae bacteremia, needing to stay in the intensive care unit for vasopressor support and targeted antibiotics.
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Aortoiliac occlusive disease Degos disease Xrteriosclerosis Fibromuscular dysplasia Raynaud’s phenomenon. Electromyography plus conduction velocities of the 4 extremities was performed, evidencing a chronic axonal sensorimotor polyneuropathy, denervation with increased amplitude of motor unit action potentials and neuropathic recruitment in distal muscles. All authors have equally contributed in the preparation and revision of the manuscript. Published online Apr The concomitant atherosclerotic process involving the intima layer of the femoral arteries explained the intermittent claudication and weak pulses presented by this patient.
Our patient showed no symptoms or signs of arterial insufficiency, presenting a clinical picture similar to the classical description of Monckeberg’s sclerosis.
Coronary angiogram revealed triple vessel disease. Clinically, the calcified vessel is described as a “pipe-stem” artery, which is visible on plain radiographs as “rail-tracking” of the vessel.
The development of calcification of the arteries is a normal process of aging; risk factors such as diabetes mellitus and chronic kidney disease are directly related to its progression. A pressure of 10 cm H 2 O was reached during some short periods of sleep with a very low effect on the arteriosclreosis of episodes of apnea.
Its pathophysiology is unclear, it is believed that the lesion will be produced by fatty degeneration of the smooth muscle cells of the middle layer, forming a mass that undergoes a hyaline degeneration and then it becomes calcified. Rua Estela,bloco E, conj. Other than mild hypertension detected during pre-anesthetic checkup, she had no other complications.
Monckeberg’s Arteriosclerosis in Uterine Vessels: An Unusual Presentation
She has three children, all delivered vaginally and at home. A transesophageal echocardiogram was carried out, which reported segmental contractility disorders and valve leaflets without the presence of vegetations, but with multiple atheromatous plaques in the entire aortic trajectory. Services on Demand Journal. Bone scintigram shows increased uptake arterioscllerosis 99 m Tc-methylene diphosphate in the calcified femoral arteries and on the anterior surface of the neck.
National Center for Biotechnology InformationU. Foot Ankle Int, 29pp. Recent progress in the treatment of vascular calcification.